NOVEL CEPHALOSPORIN ANTIBIOTICS AND PROCESSES FOR PREPARATION THEREOF

The present invention relates to a cephalosporin compound represented by the following general formula (I) : (see formula I) its pharmaceutically acceptable non-toxic salt, physiologically hydrolyzable ester, hydrate or solvate, or isomers thereof, in which R1 represents hydrogen or an amino-protect...

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Bibliographische Detailangaben
Hauptverfasser: LEE, TAE HEE, KIM, SE HO, YANG, DEOG HO, KIM, SAM SIK, KIM, YONG ZU, BANG, CHAN SIK, LIM, JONG CHAN, YEO, JAE HONG, KIM, MU YONG, WOO, YOUNG MIN, JEON, JAE HOON, OH, HUN SEUNG
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to a cephalosporin compound represented by the following general formula (I) : (see formula I) its pharmaceutically acceptable non-toxic salt, physiologically hydrolyzable ester, hydrate or solvate, or isomers thereof, in which R1 represents hydrogen or an amino-protecting group, R2 and R3 can be identical or different and independently of one another represent hydrogen or a hydroxy-protecting group, or R2 and R3 together can form a cyclic diol-protecting group, R4 represents hydrogen or a carboxyl-protecting group, R5, R6 and R7 independently of one another represent hydrogen, amino or substituted amino, hydroxy, alkoxy, C1-4 alkyl, carboxyl or alkoxycarbonyl, or R5 and R6 together with the carbon atoms to which they are attacked can form a C3-7 cycle, and Q represents CH or N, and to a process for preparation thereof and a pharmaceutical composition containing the compound (I) as an active ingredient.