PROCESS FOR THE ISOLATION AND PURIFICATION OF MEVINOLIN
In a process for preparing mevinolin by fermentation of a biomass in a fermentation liquor, which includes dissolving mevinolin from the biomass into the fermentation liquor, and separating the biomass from the fermentation liquor to obtain a separated fermentation liquor, separating the mevinolin f...
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creator | BAGDI, ILONA BALINT, JANOS SZEKELY, IMRE KERI, VILMOS ILKOY, EVA HOGYE, IRMA HORVATH, GYULA SZTARAY, ZSUZSANNA MATYAS, SZABOLCS ANDOR, ATTILA MORAVCSIK, IMRE SZABO, CSABA DEAK, LAJOS JAKAB, ATTILA SCHEIDL, ZSUZSANNA SZABO, ISTVAN LANG, ILDIKO DELI, ETELKA ESZENYI, LASZLO AMBRUS, GABOR KOVACS, VERA JEKKEL, ANTONIA |
description | In a process for preparing mevinolin by fermentation of a biomass in a fermentation liquor, which includes dissolving mevinolin from the biomass into the fermentation liquor, and separating the biomass from the fermentation liquor to obtain a separated fermentation liquor, separating the mevinolin from the separated fermentation liquor, and recovering the end product, the improvement which comprises carryingout the dissolving at a pH between about 7.5 and about 10, and the separating of the mevinolin is carried out at a pH between about 4.5 and about 1. |
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subjects | BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING SPIRITS VINEGAR WINE |
title | PROCESS FOR THE ISOLATION AND PURIFICATION OF MEVINOLIN |
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