THE USE OF CAROTENOPORPHYRINS A TUMOR LOCALIZING AGENTS FOR DIAGNOSIS, VISUALIZATION AND DELIVERY OF SENSITIZERS TO TUMOR TISSUES

2126436 9408631 PCTABS00032 A process of tumor identification comprising administering a carotenoporphyrin to a tumor-bearing mammalian host and irradiating the mammalian host with light whereupon the carotenoporphyrin, which has been preferentially taken up by the tumor tissue, fluoresces and permi...

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Hauptverfasser: JORI, GIULIO, MOORE, ANA L, REDDI, ELENA, GUST, JOHN D., JR, MOORE, THOMAS A
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:2126436 9408631 PCTABS00032 A process of tumor identification comprising administering a carotenoporphyrin to a tumor-bearing mammalian host and irradiating the mammalian host with light whereupon the carotenoporphyrin, which has been preferentially taken up by the tumor tissue, fluoresces and permits precise identification of the location, size and shape of the tumor tissue. An improved process of synthesizing carotenoporphyrins 1-5 is also provided.