N-ACETYLGLUCOSAMINYLTRANSFERASE V CODING SEQUENCES

The present invention provides a substantially purified UDP-N- acetylglucosamine:.alpha.-6-D-mannoside .beta.-1,6-N-acetylgluco- saminyltransferase (GlcNAcT-V; EC 2:4.1:155) and antibodies which specifical ly bind GlcNAc T-V. The present invention also provides polynucleotide sequences and oligonucl...

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Hauptverfasser: PIERCE, J. MICHAEL, FREGIEN, NEVIS L, ADLER, BEVERLY S, SHOREIBAH, MOHAMED G
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention provides a substantially purified UDP-N- acetylglucosamine:.alpha.-6-D-mannoside .beta.-1,6-N-acetylgluco- saminyltransferase (GlcNAcT-V; EC 2:4.1:155) and antibodies which specifical ly bind GlcNAc T-V. The present invention also provides polynucleotide sequences and oligonucleotide probes capable of specifically hybridizing to nucleic acid sequences which encode GlcNAc T-V, and cDNA and genomic clones encoding GlcNAc T-V, as well as nucleotide sequences encoding GlcNAc T-V, as: specifically exemplified by, a GlcNAd T-V coding sequence from ra t.