OLIGORIBONUCLEOTIDE AND RIBOZYME ANALOGS WITH TERMINAL 3'-3' AND/OR 5'-5' LINKAGES

of the disclosure The invention relates to oligoribonucleotide analogs with terminal 3'-3' and/or 5'-5' internucleotide linkages. This modification stabilizes the molecules altered in this way, including ribozymes, without adversely altering their properties, including, where app...

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Bibliographische Detailangaben
Hauptverfasser:	ROESCH, RUDI, ORTIGAO, FLAVIO R, BERND, KRIST, SELIGER, HEINZ H, ROESCH, HANNELORE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS SUGARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	of the disclosure The invention relates to oligoribonucleotide analogs with terminal 3'-3' and/or 5'-5' internucleotide linkages. This modification stabilizes the molecules altered in this way, including ribozymes, without adversely altering their properties, including, where appropriate, catalytic activities.