DECAHYDROISOQUINOLINES AS EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS
This invention provides novel decahydroisoquinoline compounds of the formula (See formula I) which are useful as excitatory amino acid receptor antagonists and in the treatment of neuroglogical disorders. This invention also provides synthetic methods for preparing decahydroisoquinolines, as well as...
Gespeichert in:
Hauptverfasser: | , , , , , , , , , |
---|---|
Format: | Patent |
Sprache: | eng ; fre |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | ARNOLD, MACKLIN BRIAN HANSEN, MARVIN MARTIN SCHOEPP, DARRYLE DARWIN AUGENSTEIN, NANCY KAY ORNSTEIN, PAUL LESLIE MARTINELLI, MICHAEL JOHN BERTSCH, CARL FRANKLIN HARKNESS, ALLEN ROBERT HUFF, BRET EUGENE LUNN, WILLIAM HENRY WALKER |
description | This invention provides novel decahydroisoquinoline compounds of the formula (See formula I) which are useful as excitatory amino acid receptor antagonists and in the treatment of neuroglogical disorders. This invention also provides synthetic methods for preparing decahydroisoquinolines, as well as, novel intermediates in the synthesis thereof. |
format | Patent |
fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CA2104909C</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CA2104909C</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CA2104909C3</originalsourceid><addsrcrecordid>eNrjZHBxcXV29Ih0CfL3DPYPDPX08_fx9HMNVnAMVnCNcPYMcQzxD4pUcPQFSig4Onu6KAS5OrsGAAUVHP1CHN39_TyDQ4J5GFjTEnOKU3mhNDeDvJtriLOHbmpBfnxqcUFicmpeakm8s6ORoYGJpYGlszFhFQDsbStc</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>DECAHYDROISOQUINOLINES AS EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS</title><source>esp@cenet</source><creator>ARNOLD, MACKLIN BRIAN ; HANSEN, MARVIN MARTIN ; SCHOEPP, DARRYLE DARWIN ; AUGENSTEIN, NANCY KAY ; ORNSTEIN, PAUL LESLIE ; MARTINELLI, MICHAEL JOHN ; BERTSCH, CARL FRANKLIN ; HARKNESS, ALLEN ROBERT ; HUFF, BRET EUGENE ; LUNN, WILLIAM HENRY WALKER</creator><creatorcontrib>ARNOLD, MACKLIN BRIAN ; HANSEN, MARVIN MARTIN ; SCHOEPP, DARRYLE DARWIN ; AUGENSTEIN, NANCY KAY ; ORNSTEIN, PAUL LESLIE ; MARTINELLI, MICHAEL JOHN ; BERTSCH, CARL FRANKLIN ; HARKNESS, ALLEN ROBERT ; HUFF, BRET EUGENE ; LUNN, WILLIAM HENRY WALKER</creatorcontrib><description>This invention provides novel decahydroisoquinoline compounds of the formula (See formula I) which are useful as excitatory amino acid receptor antagonists and in the treatment of neuroglogical disorders. This invention also provides synthetic methods for preparing decahydroisoquinolines, as well as, novel intermediates in the synthesis thereof.</description><edition>5</edition><language>eng ; fre</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050111&DB=EPODOC&CC=CA&NR=2104909C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050111&DB=EPODOC&CC=CA&NR=2104909C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ARNOLD, MACKLIN BRIAN</creatorcontrib><creatorcontrib>HANSEN, MARVIN MARTIN</creatorcontrib><creatorcontrib>SCHOEPP, DARRYLE DARWIN</creatorcontrib><creatorcontrib>AUGENSTEIN, NANCY KAY</creatorcontrib><creatorcontrib>ORNSTEIN, PAUL LESLIE</creatorcontrib><creatorcontrib>MARTINELLI, MICHAEL JOHN</creatorcontrib><creatorcontrib>BERTSCH, CARL FRANKLIN</creatorcontrib><creatorcontrib>HARKNESS, ALLEN ROBERT</creatorcontrib><creatorcontrib>HUFF, BRET EUGENE</creatorcontrib><creatorcontrib>LUNN, WILLIAM HENRY WALKER</creatorcontrib><title>DECAHYDROISOQUINOLINES AS EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS</title><description>This invention provides novel decahydroisoquinoline compounds of the formula (See formula I) which are useful as excitatory amino acid receptor antagonists and in the treatment of neuroglogical disorders. This invention also provides synthetic methods for preparing decahydroisoquinolines, as well as, novel intermediates in the synthesis thereof.</description><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2005</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHBxcXV29Ih0CfL3DPYPDPX08_fx9HMNVnAMVnCNcPYMcQzxD4pUcPQFSig4Onu6KAS5OrsGAAUVHP1CHN39_TyDQ4J5GFjTEnOKU3mhNDeDvJtriLOHbmpBfnxqcUFicmpeakm8s6ORoYGJpYGlszFhFQDsbStc</recordid><startdate>20050111</startdate><enddate>20050111</enddate><creator>ARNOLD, MACKLIN BRIAN</creator><creator>HANSEN, MARVIN MARTIN</creator><creator>SCHOEPP, DARRYLE DARWIN</creator><creator>AUGENSTEIN, NANCY KAY</creator><creator>ORNSTEIN, PAUL LESLIE</creator><creator>MARTINELLI, MICHAEL JOHN</creator><creator>BERTSCH, CARL FRANKLIN</creator><creator>HARKNESS, ALLEN ROBERT</creator><creator>HUFF, BRET EUGENE</creator><creator>LUNN, WILLIAM HENRY WALKER</creator><scope>EVB</scope></search><sort><creationdate>20050111</creationdate><title>DECAHYDROISOQUINOLINES AS EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS</title><author>ARNOLD, MACKLIN BRIAN ; HANSEN, MARVIN MARTIN ; SCHOEPP, DARRYLE DARWIN ; AUGENSTEIN, NANCY KAY ; ORNSTEIN, PAUL LESLIE ; MARTINELLI, MICHAEL JOHN ; BERTSCH, CARL FRANKLIN ; HARKNESS, ALLEN ROBERT ; HUFF, BRET EUGENE ; LUNN, WILLIAM HENRY WALKER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2104909C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2005</creationdate><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ARNOLD, MACKLIN BRIAN</creatorcontrib><creatorcontrib>HANSEN, MARVIN MARTIN</creatorcontrib><creatorcontrib>SCHOEPP, DARRYLE DARWIN</creatorcontrib><creatorcontrib>AUGENSTEIN, NANCY KAY</creatorcontrib><creatorcontrib>ORNSTEIN, PAUL LESLIE</creatorcontrib><creatorcontrib>MARTINELLI, MICHAEL JOHN</creatorcontrib><creatorcontrib>BERTSCH, CARL FRANKLIN</creatorcontrib><creatorcontrib>HARKNESS, ALLEN ROBERT</creatorcontrib><creatorcontrib>HUFF, BRET EUGENE</creatorcontrib><creatorcontrib>LUNN, WILLIAM HENRY WALKER</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ARNOLD, MACKLIN BRIAN</au><au>HANSEN, MARVIN MARTIN</au><au>SCHOEPP, DARRYLE DARWIN</au><au>AUGENSTEIN, NANCY KAY</au><au>ORNSTEIN, PAUL LESLIE</au><au>MARTINELLI, MICHAEL JOHN</au><au>BERTSCH, CARL FRANKLIN</au><au>HARKNESS, ALLEN ROBERT</au><au>HUFF, BRET EUGENE</au><au>LUNN, WILLIAM HENRY WALKER</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DECAHYDROISOQUINOLINES AS EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS</title><date>2005-01-11</date><risdate>2005</risdate><abstract>This invention provides novel decahydroisoquinoline compounds of the formula (See formula I) which are useful as excitatory amino acid receptor antagonists and in the treatment of neuroglogical disorders. This invention also provides synthetic methods for preparing decahydroisoquinolines, as well as, novel intermediates in the synthesis thereof.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | eng ; fre |
recordid | cdi_epo_espacenet_CA2104909C |
source | esp@cenet |
subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | DECAHYDROISOQUINOLINES AS EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-19T06%3A11%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=ARNOLD,%20MACKLIN%20BRIAN&rft.date=2005-01-11&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECA2104909C%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |