DECAHYDROISOQUINOLINES AS EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS

This invention provides novel decahydroisoquinoline compounds of the formula (See formula I) which are useful as excitatory amino acid receptor antagonists and in the treatment of neuroglogical disorders. This invention also provides synthetic methods for preparing decahydroisoquinolines, as well as...

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Hauptverfasser: ARNOLD, MACKLIN BRIAN, HANSEN, MARVIN MARTIN, SCHOEPP, DARRYLE DARWIN, AUGENSTEIN, NANCY KAY, ORNSTEIN, PAUL LESLIE, MARTINELLI, MICHAEL JOHN, BERTSCH, CARL FRANKLIN, HARKNESS, ALLEN ROBERT, HUFF, BRET EUGENE, LUNN, WILLIAM HENRY WALKER
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:This invention provides novel decahydroisoquinoline compounds of the formula (See formula I) which are useful as excitatory amino acid receptor antagonists and in the treatment of neuroglogical disorders. This invention also provides synthetic methods for preparing decahydroisoquinolines, as well as, novel intermediates in the synthesis thereof.