VITAMIN D COMPOUNDS AND METHOD OF PREPARING THESE COMPOUNDS

The invention relates to a new vitamin D compound of the general formula wherein: R1 is a hydrogen atom or a hydroxy group; R2 is a (C1-C3)alkyl group, a hydroxy(C1-C3)alkyl group, a (C1-C2) alkoxymethyl group or a (C2-C3) alkenyl or alkynyl group; R3 is a branched or non-branched, saturated or unsa...

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Bibliographische Detailangaben
Hauptverfasser:	SESTELO, JOSE P, ZORGDRAGER, JAN, MOURINO, ANTONIO, MASCARENAS, JOSE, VAN DE VELDE, JAN-PAUL, HALKES, SEBASTIANUS J, DIJKSTRA, GERHARDUS D.H
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to a new vitamin D compound of the general formula wherein: R1 is a hydrogen atom or a hydroxy group; R2 is a (C1-C3)alkyl group, a hydroxy(C1-C3)alkyl group, a (C1-C2) alkoxymethyl group or a (C2-C3) alkenyl or alkynyl group; R3 is a branched or non-branched, saturated or unsaturated aliphatic 3- to 5-membered hydrocarbon or oxahydrocarbon biradical, having at least 3 atoms in the main chain and being optionally substituted with one or more substituents selected from epoxy, fluoro and hydroxy; R4 is a sec. or tert. (C3-C6)alkyl group or a (C3-C6)cycloalkyl group; and A and B are each individually hydrogen atoms or methyl groups, or A and B form together a methylene group. The invention further relates to a method of preparing these compounds and to their use in pharmacotherapy and cosmetics.