COMPLEXES OF NITRIC OXIDE WITH POLYAMINES

There are disclosed novel complexes of nitric oxide and polyamines which are useful in treating cardiovascular disorders, including hypertension. The disclosed compounds release nitric oxide (endothelium-derived relaxing factor) under pysiological conditions in a sustained and controllable fashion,...

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Bibliographische Detailangaben
Hauptverfasser:	KEEFER, LARRY KAY, HRABIE, JOSEPH ANTHONY
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY COMPOUNDS THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE INORGANIC CHEMISTRY MEDICAL OR VETERINARY SCIENCE METALLURGY NON-METALLIC ELEMENTS ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	There are disclosed novel complexes of nitric oxide and polyamines which are useful in treating cardiovascular disorders, including hypertension. The disclosed compounds release nitric oxide (endothelium-derived relaxing factor) under pysiological conditions in a sustained and controllable fashion, and possess long mechanisms of action.