STABLE COMPOSITIONS FOR PARENTERAL ADMINISTRATION AND THEIR USE

31,672-00 STABLE COMPOSITIONS FOR PARENTERAL ADMINISTRATION AND THEIR USE The invention relates to certain stable microsphere compositions containing a fat or wax or mixture thereof; an active ingredient selected from LL-F28249.alpha.-? compounds, 23-oxo and 23-imino derivatives of LL-F28249.alpha.-...

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Bibliographische Detailangaben
Hauptverfasser: STEBER, WILLIAM D, DOSCHER, MARY E, CADY, SUSAN M, SCHWINGHAMMER, KURT A, HAYES, PHILLIP W
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:31,672-00 STABLE COMPOSITIONS FOR PARENTERAL ADMINISTRATION AND THEIR USE The invention relates to certain stable microsphere compositions containing a fat or wax or mixture thereof; an active ingredient selected from LL-F28249.alpha.-? compounds, 23-oxo and 23-imino derivatives of LL-F28249.alpha.-? compounds, milbemycin compounds and avermectin compounds; an oil, semi-soft, fatty acid derivation or mixture thereof; and an antioxidant. The invention also relates to a method for introducing and maintaining levels of the active compound in the blood of warm-blooded animals for extended periods of time and for the prevention or treatment of infections and infestations caused by helminths, nematodes, acarids and endo- and ectoparasitic arthropods in warm-blooded animals by the parenteral administration of compositions of the invention.