METHOD FOR DIAGNOSING NEURODEGENERATIVE DISEASES

2070812 9109311 PCTABS00005 Provided is a method for diagnosing in a living person an ubiquitin-associated neurodegenerative disease, such as Alzheimer's Disease, Pick's Disease, Parkinson's Disease or progressive supranuclear palsy. The method comprises assaying an aliquot of cerebra...

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Bibliographische Detailangaben
1. Verfasser:	COPPARD, NICHOLAS J
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
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Zusammenfassung:	2070812 9109311 PCTABS00005 Provided is a method for diagnosing in a living person an ubiquitin-associated neurodegenerative disease, such as Alzheimer's Disease, Pick's Disease, Parkinson's Disease or progressive supranuclear palsy. The method comprises assaying an aliquot of cerebral spinal fluid from the person for ubiquitin-immunoreactive substances. The invention rests on the surprising discovery that, in living persons with such diseases, but not in living persons without such diseases, there is a significant amount of ubiquitin-immunoreactive substances in the cerebrospinal fluid.