RECEPTOR INFECTION ASSAY

2067216 9106677 PCTABS00005 The presente invention relates to improvements in a bioassay useful for identifying materials that function as ligands for a hormone or hormone-like receptor protein measured by means of induction of reporter DNA driven by a promoter of a hormone response element. The imp...

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Bibliographische Detailangaben
1. Verfasser:	WEINBERGER, CARY A
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Zusammenfassung:	2067216 9106677 PCTABS00005 The presente invention relates to improvements in a bioassay useful for identifying materials that function as ligands for a hormone or hormone-like receptor protein measured by means of induction of reporter DNA driven by a promoter of a hormone response element. The improvement comprises producing a cell operatively harboring DNA encoding reporter gene and receptor gene by coinfection of a mammalian cell with a viral expression vector. The expedient of this invention permits commercial realization and exploitation of the bioassay system.