MACROLIDES FOR THE TREATMENT OF REVERSIBLE OBSTRUCTIVE AIR-WAYS DISEASES
Compounds of formula (I), wherein R1 and R2 together represent two vicinal hydrogen atoms, or form a second bond between the vicinal carbon atoms to which they are attached; R3 represents H , OH, alkoxy or protected hydroxy; R4 repres- ents OH; R5 represents H, alkyl or alkenyl; R6 and R7 independen...
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Format: | Patent |
Sprache: | eng ; fre |
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Zusammenfassung: | Compounds of formula (I), wherein R1 and R2 together represent two vicinal hydrogen atoms, or form a second bond between the vicinal carbon atoms to which they are attached; R3 represents H , OH, alkoxy or protected hydroxy; R4 repres- ents OH; R5 represents H, alkyl or alkenyl; R6 and R7 independently represen t O, (H,OH), (H,protected hydroxy) or (H,al- koxy); X and Y independently represent O, (H,OH) or (H,H); n is 1 or 2; or pharmaceutically acceptable derivatives there- of; are provided for the treatment of reversible obstructive airways disease , particularly asthma. Compositions containing such compounds are also disclosed. |
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