IMPROVED IMMUNOASSAY INCLUDING LYOPHILIZED REACTANT MIXTURE

IMPROVED IMMUNOASSAY INCLUDING LYOPHILIZED REACTANT MIXTURE A lypphilized mixture of reactants for an immunoassay includes antibody-gold sol particle conjugates, antibody latex particle conjugates, polyethylene glycol p-isooctylphenyl ether detergent and dextrin or trehalose. The polyethylene glycol...

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Bibliographische Detailangaben
1. Verfasser: COLE, FRANCIS X
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:IMPROVED IMMUNOASSAY INCLUDING LYOPHILIZED REACTANT MIXTURE A lypphilized mixture of reactants for an immunoassay includes antibody-gold sol particle conjugates, antibody latex particle conjugates, polyethylene glycol p-isooctylphenyl ether detergent and dextrin or trehalose. The polyethylene glycol is present to enhance binding of the immunoreactants and the polyethylene glycol p-isooctylphenyl ether detergent is present to prevent non-specific interactions. The dextrin or threhalose prevents agglomeration of the polyethylent glycol and polyethylene galycol p-isooctylphenyl ether in the lyophilized mixture at room temperature and facilitates retention of homogenous distribution of the ingredients of the mixture to thereby enhance shelf life and redistribution of the mixture in an aqueous test system.