AUTOMATIC CONTROL SYSTEM FOR IMPROVED ELECTROPHORESIS

61 PATENT Attorney Docket No. 2558-397 AUTOMATIC CONTROL SYSTEM FOR IMPROVED ELECTROPHORESIS A system for improving the electrophoretic separation of macromolecules with the aid of a computer is described. The system maintains a knowledge base derived from calibration data obtained by separating mac...

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Hauptverfasser:	BERS, GEORGE E, BIRREN, BRUCE W, LAI, ERIC, STUBBLEBINE, WILL H
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS SEPARATION TESTING TRANSPORTING
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Zusammenfassung:	61 PATENT Attorney Docket No. 2558-397 AUTOMATIC CONTROL SYSTEM FOR IMPROVED ELECTROPHORESIS A system for improving the electrophoretic separation of macromolecules with the aid of a computer is described. The system maintains a knowledge base derived from calibration data obtained by separating macromolecules, in particular DNA, of known size under a variety of planned conditions chosen to optimize separations. The user enters the smallest and largest DNA sizes to be resolved. From this information, the system automatically sets the optimal Voltage Gradient, Angle, Initial Switch Time, Final Switch Time, Forward Voltage Gradient, and Reverse Voltage Gradient parameters, thereby increasing the resolution of electrophoresis.