SOLID ORAL FORMS OF APPLICATION CONTAINING IFOSFAMIDE AS ACTIVE SUBSTANCE

SOLID ORAL FORMS OF APPLICATION CONTAINING IFOSFAMIDE AS ACTIVE SUBSTANCE

Solid oral ifosfamide formulations are disclosed where the capsule mass substantially consists of the active substance ifosfamide and microcrystalline cellulase, or in the form of tablets which contain, in relation to one part by weight of ifosfamide, 0.1 - 1.0 parts by weight of tricalcium phosphat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SAUERBIER, DIETER, MILSMANN, ECKHARD, MOLGE, KLAUS, ISAAC, OTTO, ENGEL, JURGEN
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Solid oral ifosfamide formulations are disclosed where the capsule mass substantially consists of the active substance ifosfamide and microcrystalline cellulase, or in the form of tablets which contain, in relation to one part by weight of ifosfamide, 0.1 - 1.0 parts by weight of tricalcium phosphate, and 0.04 - 0.4 parts by weight of polyethylene glycol as well as in addition, related to the weight of the tablet 5 - 60 % by weight of a filling and flow regulating agent, 1 - 10 % by weight of a disintegrant, 0.1 - 10 % by weight of an antiadhesion agent, and 0.1 - 80% by weight of a binding agent.