SUBSTITUTED AROMATIC SULFONAMIDES AS ANTIGLAUCOMA AGENTS

SUBSTITUTED AROMATIC SULFONAMIDES AS ANTIGLAUCOMA AGENTS

Thieno[2,3-b]thiopyran-2-sulfonamides and ring homologs with a hydrophilic substituted-alkyl group adjacent to the thiopyran sulfur are carbonic anhydrase inhibitors topically effective in lowering intraocular pressure.

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Bibliographische Detailangaben
Hauptverfasser: PONTICELLO, GERALD S, BALDWIN, JOHN J, SELNICK, HAROLD G, HABECKER, CHARLES N
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Thieno[2,3-b]thiopyran-2-sulfonamides and ring homologs with a hydrophilic substituted-alkyl group adjacent to the thiopyran sulfur are carbonic anhydrase inhibitors topically effective in lowering intraocular pressure.