BENZISOTHIAZOLINONE-1-DIOXIDE DERIVATIVES AS ELASTASE INHIBITORS
ABSTRACT BENZISOTHIAZOLINONE-1-DIOXIDE DERIVATIVES AS ELASTASE INHIBITORS The invention relates to pharmaceutical and cosmetic compositions comprising at least one benzisothiazolinone-1-dioxide derivative with the formula: (1) where R1 can be hydrogen, and R2 can be certain generally hydrophobic C8-...
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| creator | MOCZAR, ELEMER ROBERT, LADISLAS KERNEUR, MARIE-PIERRE HORNEBECK, WILLIAM G |
| description | ABSTRACT BENZISOTHIAZOLINONE-1-DIOXIDE DERIVATIVES AS ELASTASE INHIBITORS The invention relates to pharmaceutical and cosmetic compositions comprising at least one benzisothiazolinone-1-dioxide derivative with the formula: (1) where R1 can be hydrogen, and R2 can be certain generally hydrophobic C8-C20 aliphatic groups or the group: (III) where R5 is aliphatic or else R2 is a saturated or unsaturated C2-C6 group ending in an aromatic nucleus. These compositions can be used to inhibit elastases such as human leucocytic elastase. They may be applied topically as a cosmetic. Many of the benzisothiazolinone-1-dioxide derivative specified as active ingredient in such compositions are novel compounds. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS |
| title | BENZISOTHIAZOLINONE-1-DIOXIDE DERIVATIVES AS ELASTASE INHIBITORS |
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