W-AMINO-.ALPHA.-PHENYLALKANONITRILE DERIVATIVES

W-AMINO-.ALPHA.-PHENYLALKANONITRILE DERIVATIVES

Case 2592 .omega.-AMINO-.alpha.-PHENYLALKANONITRILE DERIVATIVES ABSTRACT A class of .omega.-amino-.alpha.-phenylalkanonitrile derivatives is described having use in treatment of cardiovascular dysfunctions such as hypertension. Compounds of most interest are those of the formula: wherein each of R1...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GILLET, CLAUDE, SNYERS, MICHEL P, GORISSEN, HUGO, BOVY, PHILIPPE R
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Case 2592 .omega.-AMINO-.alpha.-PHENYLALKANONITRILE DERIVATIVES ABSTRACT A class of .omega.-amino-.alpha.-phenylalkanonitrile derivatives is described having use in treatment of cardiovascular dysfunctions such as hypertension. Compounds of most interest are those of the formula: wherein each of R1 and R2 is methoxy, R3 is hydrido, R4 is isopropyl, R5 is methyl and R6 is selected from linear alkyl, phenylpropyl, phenylbutyl and phenylpentyl.