NOVEL 8-SUBSTITUTED-2-AMINOTETRALINES

A compound of formula (I), where Z is hydrogen or halogen, Q is COR1 or 5- or 6-membered aryl which may contain 1 or 2 heteroatoms selected from N, O or S and may be substituted or fused wherein R is hydrogen or C1-methyl (cis- configuration) , R1 is C1-C6 alkyl or an aromatic ring which may contain...

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Hauptverfasser: HACKSELL, ULI ALF, HILLVER, SVEN-ERIK, YU, HONG, BJORK, ANNA LENA MARIA, VALLGARDA, KARL JERK, HOOK, BERIT CHRISTINA ELISABET BACKLUND, ANDEN, NILS-ERIK, LIU, YE, PERSSON, EVA MARIE, MELLIN, EVA CHARLOTTA
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:A compound of formula (I), where Z is hydrogen or halogen, Q is COR1 or 5- or 6-membered aryl which may contain 1 or 2 heteroatoms selected from N, O or S and may be substituted or fused wherein R is hydrogen or C1-methyl (cis- configuration) , R1 is C1-C6 alkyl or an aromatic ring which may contain heteroatoms selected from O and S and may be substituted or fused to an optionally substituted benzene ring, R2 is hydrogen or C1-C6 alkyl and R3 may be different groups defined in claim 1, and enantiomers/salts thereof, processes for preparation of said compounds, pharmaceutical preparations containing said compounds, use of and method of treatment of disorders in CNS by using said compounds.