STABILIZATION OF CARBOXYL ESTERASE

Carboxyl esterase is inactivated by several chemical compounds such as naproxen or diclofop. By substituting or modifying certain basic residues of the carboxyl esterase, this enzyme shows improved stability properties during application. In this way it is possible to perform stereospecific hydrolys...

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Bibliographische Detailangaben
Hauptverfasser: MUTSAERS, JOHANNA H. G. M, BROEKHUIZEN, CORNELIS P, VAN DER LAKEN, CORNELIS J, QUAX, WILHELMUS J
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Carboxyl esterase is inactivated by several chemical compounds such as naproxen or diclofop. By substituting or modifying certain basic residues of the carboxyl esterase, this enzyme shows improved stability properties during application. In this way it is possible to perform stereospecific hydrolysis reactions on industrial scale even at high substrate concentrations.