DEHYDROCHOLECALCIFEROL DERIVATIVES

The novel use of compounds of formula (see formula I) wherein R is H or OH, A is -C~C-, -CH=CH- with E-configuration or -CH2CH2- and R" is H or, where A is -C~C-, R" may also be deuterium, for the treatment of sebaceous gland diseases, such as seborrheic dermatitis and, particularly, acne:...

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Bibliographische Detailangaben
Hauptverfasser:	TRUITT, GARY A, HENNESSY, BERNARD M, USKOKOVIC, MILAN R, BAGGIOLINI, ENRICO G, SHIUEY, SHIAN-JAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
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Beschreibung
Zusammenfassung:	The novel use of compounds of formula (see formula I) wherein R is H or OH, A is -C~C-, -CH=CH- with E-configuration or -CH2CH2- and R" is H or, where A is -C~C-, R" may also be deuterium, for the treatment of sebaceous gland diseases, such as seborrheic dermatitis and, particularly, acne: a corresponding method of treatment as well as pharmaceutical compositions and commercial packages containing such a compound. Novel compounds of formula I, wherein R" is deuterium.