SUBSTITUTED-1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES

SUBSTITUTED-1,3-OXATHIOLANES WITH ANTIVIRAL PROPERTIES

Disclosed are compounds of the formula wherein R1 is hydrogen; R2 is a purine or pyrimidine base or an analogue or derivative thereof; Z is S, S=O or SO2; and pharmaceutically acceptable derivatives thereof. Also described are use of the compounds as antiviral agents, pharmaceutical formulations, an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: NGUYEN-BA, NGHE, BELLEAU, BERNARD (DECEASED)
Format: Patent
Sprache:eng
Schlagworte:
APPARATUS THEREFOR
CHEMISTRY
DERIVATIVES THEREOF
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Beschreibung
Zusammenfassung:Disclosed are compounds of the formula wherein R1 is hydrogen; R2 is a purine or pyrimidine base or an analogue or derivative thereof; Z is S, S=O or SO2; and pharmaceutically acceptable derivatives thereof. Also described are use of the compounds as antiviral agents, pharmaceutical formulations, and methods for the preparation of the compounds.