AROMATIC KETO COMPOUNDS, THE PREPARATION THEREOF, AND DRUGS AND COSMETICS CONTAINING THESE

Compounds of the general formula I (see formula I) where A is ethylene or methylene which can be substituted by methyl, hydroxyl or oxo, L is one of the following (see formula II) R1 and R2 are hydrogen or methyl, R3 is hydrogen, hydroxyl ar C1-C6-alkoxy, R4 ; is hydrogen, C1-C4-alkyl, halogen or me...

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Hauptverfasser: WUEST, HANS-HEINER, JANSSEN, BERND
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Sprache:eng ; fre
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Zusammenfassung:Compounds of the general formula I (see formula I) where A is ethylene or methylene which can be substituted by methyl, hydroxyl or oxo, L is one of the following (see formula II) R1 and R2 are hydrogen or methyl, R3 is hydrogen, hydroxyl ar C1-C6-alkoxy, R4 ; is hydrogen, C1-C4-alkyl, halogen or methoxy, R5 is hydrogen or methoxy, and R6 is hydrogen, methyl, cyano, a C2-C10 group of the formula (see formula III) where R',R" and R'" are each alkyl of 1 to 9 carbons, the total of carbons in R',R",R'" is 2 to 10, and R' can also be hydrogen, or the following -CHR7-OR8, -CHR7-NR9R10, -COR11, (see formula IV) or -SO2R11 where R7 is hydrogen or C1-C4-alkyl, R8 is hydrogen, C1-C4-alkyl, C1-C20-alkanoyl, or benzoyl which can be substituted, R9 and R10 are hydrogen, C1-C4-alkyl, C1-C6-alkanoyl, or benzoyl which can be substituted, or form, together with the nitrogen to which they are bonded, a 5- or 6-membered saturated heterocyclic radical which can also contain an oxygen in addition to the nitrogen, R11 is hydrogen, C1-C4-alkyl, or -OR13 or -NR14R15 where R13 is hydrogen, C1-C8-alkyl which can be substituted by 1 or 2 hydroxyls, or aryl or aralkyl each of which can be substituted in the aryl moiety, and where R14 and R15 are hydrogen, or aralkyl or aryl which can be substituted, or R14 and R15 form, together with the nitrogen to which they are banded, a 5- or 6-membered saturated heterocyclic radical which can also contain an oxygen in addition to the nitrogen, and R12 is C1-C4-alkyl, and the physiologically tolerated salts thexeof, processes far the preparation thereof, and drugs and cosmetics prepared therefrom are described.