HUMAN B LYMPHOTROPIC VIRUS (HBLV) ISOLATION AND PRODUCTS

A new human B-lymphotropic virus (HBLV) has been isolated. DNA, molecular clones, antigenic viral proteins and antibodies having specificity to the new virus have been prepared. A method for obtaining HBLV particles has the steps of growing a co-culture of infected patient blood with uninfected suit...

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Hauptverfasser:	SALAHUDDIN SYED ZAKI, GALLO, ROBERT, C
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	A new human B-lymphotropic virus (HBLV) has been isolated. DNA, molecular clones, antigenic viral proteins and antibodies having specificity to the new virus have been prepared. A method for obtaining HBLV particles has the steps of growing a co-culture of infected patient blood with uninfected suitable target cells, isolating infected cells from the culture cell cloning, multiplying the infected cells by serial transmission, isolating a virus from the infected cell culture, and concentrating the virus. Various utilities of the new virus and products derived therefrom are described. Methods for detecting the presence of HBLV in a patient suffering from acquired immune deficiency syndrome; and for detecting antibodies specific to HBLV membrane antigens in human serum suspected of being infected with HBLV are also described.