PROTEIN H BEING CAPABLE OF BINDING TO IGG, GENE CODING FOR THE SAID PROTEIN H AND A PROCESS FOR PRODUCING THE SAID PROTEIN H

A gene coding for the novel Protein H, which is capable of binding specifically to human IgG of all subclasses, was isolated from Streptococcus sp. AP1 and expressed in host cells, E. coli to produce the Protein H. The new protein is useful in the assay and purification of human IgG, removal or adso...

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Hauptverfasser: KISHIMOTO, FUMITAKA, BJOERCK, LARS, HATTORI, SHIZUO, GOMI, HIDEYUKI, HOZUMI, TATSUNOBU, TAGAWA, CHIAKI
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:A gene coding for the novel Protein H, which is capable of binding specifically to human IgG of all subclasses, was isolated from Streptococcus sp. AP1 and expressed in host cells, E. coli to produce the Protein H. The new protein is useful in the assay and purification of human IgG, removal or adsorption of excessive IgG from blood and for diagnosis of autoimmune diseases.