SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY ANTIDEGENERATIVE AGENTS

New substituted azetidinones of Formula I are found as potent elastase inhibitors and thereby useful antiinflammatory and anti-degenerative agents (I) The active substituted azetidinones can be used to provide pharmaceutical compositions as protease inhibitors useful for controlling tissue damage an...

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Bibliographische Detailangaben
Hauptverfasser:	SHAH, SHRENIK K, HAGMANN, WILLIAM, DOHERTY, JAMES B, FINKE, PAUL E, FIRESTONE, RAYMOND A, DORN, CONRAD P, BARKER, PETER L
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	New substituted azetidinones of Formula I are found as potent elastase inhibitors and thereby useful antiinflammatory and anti-degenerative agents (I) The active substituted azetidinones can be used to provide pharmaceutical compositions as protease inhibitors useful for controlling tissue damage and various inflammatory or degenerative conditions mediated by proteases particularly elastase.