AGLYCONS OF A/16686 ANTIBIOTICS

AGLYCONS OF A/16686 ANTIBIOTICS

The invention concerns the aglycons of factors A1, A2, A3, A'1, A'2, A'3 of antibiotic A/16686, their respective tetrahydroderivatives and mixtures thereof. The aglycons are produced by selective hydrolysis of the above mentioned factors. The compounds have antibacterial activity, in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CAVALLERI, BRUNO, CIABATTI, ROMEO
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention concerns the aglycons of factors A1, A2, A3, A'1, A'2, A'3 of antibiotic A/16686, their respective tetrahydroderivatives and mixtures thereof. The aglycons are produced by selective hydrolysis of the above mentioned factors. The compounds have antibacterial activity, in particular, against widely diffused gram positive bacteria and are particularly useful for topical treatment of wound infections and acne.