MIXED CRYSTALS OF INSULIN AND INSULIN DERIVATIVES, A PROCESS FOR THE PREPARATION OF THESE MIXED CRYSTALS, PHARMACEUTICAL AGENTS CONTAINING THESE MIXED CRYSTALS, AND THE USE THEREOF FOR THE TREATMENT OF DIABETES MELLITUS

MIXED CRYSTALS OF INSULIN AND INSULIN DERIVATIVES, A PROCESS FOR THE PREPARATION OF THESE MIXED CRYSTALS, PHARMACEUTICAL AGENTS CONTAINING THESE MIXED CRYSTALS, AND THE USE THEREOF FOR THE TREATMENT OF DIABETES MELLITUS

Mixed crystals composed of A. unmodified insulin, des-Phe-B1 insulin, des-Thr-B30 (human) or des-Ala-B30 (pork, beef) insulin and B. at least one insulin having a basic modification at the C-terminal end of the B chain, preferably composed of human insulin (A) and Arg-B31 human insulin and/or Arg2-(...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: DOERSCHUG, MICHAEL, OBERMEIER, RAINER
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator DOERSCHUG, MICHAEL
OBERMEIER, RAINER
description Mixed crystals composed of A. unmodified insulin, des-Phe-B1 insulin, des-Thr-B30 (human) or des-Ala-B30 (pork, beef) insulin and B. at least one insulin having a basic modification at the C-terminal end of the B chain, preferably composed of human insulin (A) and Arg-B31 human insulin and/or Arg2-(B31-32) human insulin (B) are obtained by crystallization from aqueous solution within a narrow pH range (from about 5.5 to about 6.9). The mixed crystals show a specific moderately prolonged profile and are suitable for the treatment of diabetes mellitus.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CA1335924C</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CA1335924C</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CA1335924C3</originalsourceid><addsrcrecordid>eNqFjrFuwkAMhrN0QC3PgB8gHUpgYHQvDrF0uYvOTgQTQtV1qtpI6dvyMlwkQGJATL_t3_4_z7JTwzsqwYS9KFoBXwE76Sw7QFfe6pIC96jck-SA0AZvSAQqH0BrSj21GJLv3ZSQRkJwn5xDW2No0FCnbNACbsmpgPFOkR277YOz6Y2J0SUvaaAEuHI1EGqTciZqyfhJSgINWcvayVv28n38GeP8oq_ZoiI19Xsc_g5xHI5f8Tf-Hwx-FMV6s1yZ4vnGGdv_VAo</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>MIXED CRYSTALS OF INSULIN AND INSULIN DERIVATIVES, A PROCESS FOR THE PREPARATION OF THESE MIXED CRYSTALS, PHARMACEUTICAL AGENTS CONTAINING THESE MIXED CRYSTALS, AND THE USE THEREOF FOR THE TREATMENT OF DIABETES MELLITUS</title><source>esp@cenet</source><creator>DOERSCHUG, MICHAEL ; OBERMEIER, RAINER</creator><creatorcontrib>DOERSCHUG, MICHAEL ; OBERMEIER, RAINER</creatorcontrib><description>Mixed crystals composed of A. unmodified insulin, des-Phe-B1 insulin, des-Thr-B30 (human) or des-Ala-B30 (pork, beef) insulin and B. at least one insulin having a basic modification at the C-terminal end of the B chain, preferably composed of human insulin (A) and Arg-B31 human insulin and/or Arg2-(B31-32) human insulin (B) are obtained by crystallization from aqueous solution within a narrow pH range (from about 5.5 to about 6.9). The mixed crystals show a specific moderately prolonged profile and are suitable for the treatment of diabetes mellitus.</description><edition>5</edition><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1995</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19950613&amp;DB=EPODOC&amp;CC=CA&amp;NR=1335924C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19950613&amp;DB=EPODOC&amp;CC=CA&amp;NR=1335924C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DOERSCHUG, MICHAEL</creatorcontrib><creatorcontrib>OBERMEIER, RAINER</creatorcontrib><title>MIXED CRYSTALS OF INSULIN AND INSULIN DERIVATIVES, A PROCESS FOR THE PREPARATION OF THESE MIXED CRYSTALS, PHARMACEUTICAL AGENTS CONTAINING THESE MIXED CRYSTALS, AND THE USE THEREOF FOR THE TREATMENT OF DIABETES MELLITUS</title><description>Mixed crystals composed of A. unmodified insulin, des-Phe-B1 insulin, des-Thr-B30 (human) or des-Ala-B30 (pork, beef) insulin and B. at least one insulin having a basic modification at the C-terminal end of the B chain, preferably composed of human insulin (A) and Arg-B31 human insulin and/or Arg2-(B31-32) human insulin (B) are obtained by crystallization from aqueous solution within a narrow pH range (from about 5.5 to about 6.9). The mixed crystals show a specific moderately prolonged profile and are suitable for the treatment of diabetes mellitus.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1995</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFjrFuwkAMhrN0QC3PgB8gHUpgYHQvDrF0uYvOTgQTQtV1qtpI6dvyMlwkQGJATL_t3_4_z7JTwzsqwYS9KFoBXwE76Sw7QFfe6pIC96jck-SA0AZvSAQqH0BrSj21GJLv3ZSQRkJwn5xDW2No0FCnbNACbsmpgPFOkR277YOz6Y2J0SUvaaAEuHI1EGqTciZqyfhJSgINWcvayVv28n38GeP8oq_ZoiI19Xsc_g5xHI5f8Tf-Hwx-FMV6s1yZ4vnGGdv_VAo</recordid><startdate>19950613</startdate><enddate>19950613</enddate><creator>DOERSCHUG, MICHAEL</creator><creator>OBERMEIER, RAINER</creator><scope>EVB</scope></search><sort><creationdate>19950613</creationdate><title>MIXED CRYSTALS OF INSULIN AND INSULIN DERIVATIVES, A PROCESS FOR THE PREPARATION OF THESE MIXED CRYSTALS, PHARMACEUTICAL AGENTS CONTAINING THESE MIXED CRYSTALS, AND THE USE THEREOF FOR THE TREATMENT OF DIABETES MELLITUS</title><author>DOERSCHUG, MICHAEL ; OBERMEIER, RAINER</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA1335924C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>1995</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>DOERSCHUG, MICHAEL</creatorcontrib><creatorcontrib>OBERMEIER, RAINER</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DOERSCHUG, MICHAEL</au><au>OBERMEIER, RAINER</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>MIXED CRYSTALS OF INSULIN AND INSULIN DERIVATIVES, A PROCESS FOR THE PREPARATION OF THESE MIXED CRYSTALS, PHARMACEUTICAL AGENTS CONTAINING THESE MIXED CRYSTALS, AND THE USE THEREOF FOR THE TREATMENT OF DIABETES MELLITUS</title><date>1995-06-13</date><risdate>1995</risdate><abstract>Mixed crystals composed of A. unmodified insulin, des-Phe-B1 insulin, des-Thr-B30 (human) or des-Ala-B30 (pork, beef) insulin and B. at least one insulin having a basic modification at the C-terminal end of the B chain, preferably composed of human insulin (A) and Arg-B31 human insulin and/or Arg2-(B31-32) human insulin (B) are obtained by crystallization from aqueous solution within a narrow pH range (from about 5.5 to about 6.9). The mixed crystals show a specific moderately prolonged profile and are suitable for the treatment of diabetes mellitus.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre
recordid cdi_epo_espacenet_CA1335924C
source esp@cenet
subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title MIXED CRYSTALS OF INSULIN AND INSULIN DERIVATIVES, A PROCESS FOR THE PREPARATION OF THESE MIXED CRYSTALS, PHARMACEUTICAL AGENTS CONTAINING THESE MIXED CRYSTALS, AND THE USE THEREOF FOR THE TREATMENT OF DIABETES MELLITUS
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T13%3A10%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=DOERSCHUG,%20MICHAEL&rft.date=1995-06-13&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECA1335924C%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true