ANTICHOLINERGIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHOD OF TREATMENT

A compound having the formula - - - - (I) Wherein: R1 is the esterification residue of a pharmaceutically acceptable non-toxic, substituted or unsubstituted, straight cyclic or branched chain alcohol (R1-OH) having from 1 to 8 carbon atoms such that the ester group, COOR1, is metabolically hydrolyzable to the free alcohol, R1-OH, and a non-toxic metabolite of said compound following administration thereof to a human or non-human animal; R2 is a substituted or unsubstituted aryl, cycloalkyl or alkyl group having from 1 to 8 carbon atoms; R3 is H or R2; n is an integer from 0 to 4; X is ; , wherein R8 is H or straight or branched chain alkyl having from 1 to 5 carbon atoms; ; , wherein R9 and R10 may be the same or different and may be H or lower alkyl having from 1 to 5 carbon atoms; ; or ; m is an integer from 0 to 4; R4 is or , wherein R5 and R6 may be the same or different and are alkyls having from 1 to 5 carbon atoms; or wherein R5, R6 and R7 may be the same or different and are alkyls having from 1 to 5 carbon atoms; ortho-, meta- or para- substituted alkyl pyridine, wherein Z is an integer from 0 to 3 or wherein said empty valences are filled with groups to produce a non-toxic quaternary nitrogen salt and X- is a pharmaceutically acceptable anion; said substituents rendering said compound non-toxic, and said compound exhibiting anticholinergic or mydriatic properties.