INSTANT ORAL-RELEASE CAPSULE CONTAINING NIFEDIPINE

A b s t r a c t The invention concerns an instant oral-release capsule containing an aqueous or aqueous alcoholic solution of nifedipine, containing a polyalkylene glycol and a polyoxyethylene ester component, the amount of the ester component in the solution being sufficient to prevent precipitatio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser:	WIMMER, WALTER
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A b s t r a c t The invention concerns an instant oral-release capsule containing an aqueous or aqueous alcoholic solution of nifedipine, containing a polyalkylene glycol and a polyoxyethylene ester component, the amount of the ester component in the solution being sufficient to prevent precipitation of nifedipine in the mouth of a patient after release of the solution from the capsule. Preferably, the ester component. is an ethoxylated hydrogenated castor oil Cremophor* RH40. The solution may further contain a second glycol component, especially glycerol. * Trade-Mark