ANTI-MELANOMA ANTIBODY MG-21 FOR DIAGNOSIS AND THERAPY OF HUMAN TUMORS

An antibody MG-21 which is directed against a tumorassociated glycolipid antigen and which is capable of activating serum complement or antibody dependent cellular cytotoxicity is described. This antibody finds use in the therapy of cancers particularly melanoma and glioma. Proper administration of...

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Bibliographische Detailangaben
Hauptverfasser:	HELLSTROM, KARL E, HELLSTROM, INGEGERD
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS METALLURGY ORGANIC CHEMISTRY PEPTIDES TECHNICAL SUBJECTS COVERED BY FORMER USPC TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ARTCOLLECTIONS [XRACs] AND DIGESTS
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Beschreibung
Zusammenfassung:	An antibody MG-21 which is directed against a tumorassociated glycolipid antigen and which is capable of activating serum complement or antibody dependent cellular cytotoxicity is described. This antibody finds use in the therapy of cancers particularly melanoma and glioma. Proper administration of the antibody results in lysis of the tumor cells in vivo.