ESTERS OF N-ALKYL-NORTROPINES AND THEIR QUATERNARY DERIVATIVES HAVING ANTI-BRONCHOSPASTIC ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

ESTERS OF N-ALKYL-NORTROPINES AND THEIR QUATERNARY DERIVATIVES HAVING ANTI-BRONCHOSPASTIC ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

"Esters of N-alKyl-nortropines and their quaternary derivatives having anti-bronchospastic activity, process for their prepararation and pharmaceutical compositions containing them" The esters of M-alkyl-nortropines with phenyl-cyclohexen-carboxylic and phenyl-cyclohexen-acetic acids and t...

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Bibliographische Detailangaben
Hauptverfasser: CERBAI, GUIDO, TURBANTI, LUIGI
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:"Esters of N-alKyl-nortropines and their quaternary derivatives having anti-bronchospastic activity, process for their prepararation and pharmaceutical compositions containing them" The esters of M-alkyl-nortropines with phenyl-cyclohexen-carboxylic and phenyl-cyclohexen-acetic acids and their quaternary ammonium derivatives with alkyl halides and alkyl sulphates having general formula: Xwherein when A= R= -CH2-CH3 -CH2-CH2-CH3 -CH(CH3)2 and when A= R= -CH3 -CH2-CH3 -CH2-CH2-CH3 -CH(CH3)2 whereas R'= -, -H, -CH3, -CH2-CH3, -CH2-CH2-CH3, -CH(CH3)2, -CH2-CH2-CH2-CH3, -CH2-CH-(CH3)2 X-= Cl, Br, J, CH3SO4 show anti-bronchospastic activity. The invention relates also to the processes for their preparation and to the pharmaceutical compositions containing them.