PROCESS FOR THE PREPARATION OF 2-HALOGENATED ERGOLINE DERIVATIVES

PROCESS FOR THE PREPARATION OF 2-HALOGENATED ERGOLINE DERIVATIVES The invention relates to a novel process for the halogenation in 2-position of ergot alkaloids. The process is characterized by that as a halogenating agent a system consisting of dimethylsulfoxide, a trialkylhalosilane or triarylhalo...

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Hauptverfasser: KEVE, TIBOR, MEGYERI, GABOR, SZEPESI, GABOR, KOVACS, LAJOS, JR, GAZDAG, MARIA, TRISCHLER, FERENC, STEFKO, BELA, BOGSCH, ERIK, KASSAI, ANNA NEE ZIEGER
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:PROCESS FOR THE PREPARATION OF 2-HALOGENATED ERGOLINE DERIVATIVES The invention relates to a novel process for the halogenation in 2-position of ergot alkaloids. The process is characterized by that as a halogenating agent a system consisting of dimethylsulfoxide, a trialkylhalosilane or triarylhalosilane and optionally a hydrogen halide is used. A 3999-67/MR