BINDER COMPOSITION AND ANALYTICAL ELEMENT HAVING STABILIZED PEROXIDASE IN LAYER CONTAINING THE COMPOSITION

BINDER COMPOSITION AND ANALYTICAL ELEMENT HAVING STABILIZED PEROXIDASE IN LAYER CONTAINING THE COMPOSITION An analytical element has a peroxidaselabeled ligand analog distributed within a layer comprising from 0.1 to 10.0 y/m2 of poly(vinylalcohol) and from 0.2 to 20.0 g/m2 of glycerol. The concentr...

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1. Verfasser: EIKENBERRY, JON N
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:BINDER COMPOSITION AND ANALYTICAL ELEMENT HAVING STABILIZED PEROXIDASE IN LAYER CONTAINING THE COMPOSITION An analytical element has a peroxidaselabeled ligand analog distributed within a layer comprising from 0.1 to 10.0 y/m2 of poly(vinylalcohol) and from 0.2 to 20.0 g/m2 of glycerol. The concentration of the glycerol must be greater than 1 times the concentration of poly(vinylalcohol) in the layer. As a result, the peroxidase retains more of its stability prior to use. Such elements can be used to determine a number of different immunologically reactive analytes, such as digoxin.