PROCESS FOR PREPARING SUBSTITUTED ANTHRA [1,9- CD]PYRAZOL-6(1H)-ONES

PROCESS FOR PREPARING SUBSTITUTED ANTHRA [1,9- CD]PYRAZOL-6(1H)-ONES

An improved process for producing anthra¢1,9-cd!-pyrazol-6(2H)-ones from 1,4-dichloro-5,8-disubstituted 9,10-anthracenediones. The process produces higher yields by using a new combination of protecting groups on the compounds which allows for easier and cleaner chromatographic resolution. The compo...

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Bibliographische Detailangaben
Hauptverfasser: SHOWALTER, HOWARD D.H, GOEL, OM P, BEYLIN, VLADIMIR G
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:An improved process for producing anthra¢1,9-cd!-pyrazol-6(2H)-ones from 1,4-dichloro-5,8-disubstituted 9,10-anthracenediones. The process produces higher yields by using a new combination of protecting groups on the compounds which allows for easier and cleaner chromatographic resolution. The compounds produced have antibacterial, antifungal, antileukemic, and antitumor activity.