DERIVATIVES OF IMIDAZOLE, THEIR PREPARATION AND UTILISATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES

DERIVATIVES OF IMIDAZOLE, THEIR PREPARATION AND UTILISATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES

Derivatives of imidazole corresponding to formula I wherein X1, X2, Y1 and Y2, whether or not identical, can have different significancies, R1 is hydrogen, a methyl or phenyl group, R2 and R3, whether or not identical, represent hydrogen, a hydroxyl, alkyl or alkoxy group, it being possible for R1 a...

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Bibliographische Detailangaben
Hauptverfasser: CORDI, ALEXIS A, CALDERON, PIEDAD, ROBA, JOSEPH L, GORISSEN, HUGO J, LAMBELIN, GEORGES E, SNYERS, MICHEL P, VAN DORSSER, WILLIAM R, GILLET, CLAUDE L
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Derivatives of imidazole corresponding to formula I wherein X1, X2, Y1 and Y2, whether or not identical, can have different significancies, R1 is hydrogen, a methyl or phenyl group, R2 and R3, whether or not identical, represent hydrogen, a hydroxyl, alkyl or alkoxy group, it being possible for R1 and R2 together to represent a carbon-carbon bond, R4 and R5, whether or not identical, being hydrogen or alkyl, and the tautomers and salts of these compounds, also the pharmaceutical compositions containing them. The compounds are endowed with .alpha.2-blocking and/or anticonvulsive activities and are utilisable as therapeutic agents for man.