PHARMACEUTICAL COMPOSITIONS CONTAINING DIHYDROPYRIDINE

PHARMACEUTICAL COMPOSITIONS CONTAINING DIHYDROPYRIDINE

An antihypertensive and antianginal combination comprising (A) 0.1 to 10 parts by weight of an asymmetrical dihydropyridine of the formula in which R1 and R5 each independently is methyl, hydroxymethyl or cyano, R2 and R4 are always different from one another and each independently is alkyl with 1 t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SCHLUUETER, GERHARD, GROSS, RAINER, SCHRAMM, MATTHIAS, KAZDA, STANISLAV
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:An antihypertensive and antianginal combination comprising (A) 0.1 to 10 parts by weight of an asymmetrical dihydropyridine of the formula in which R1 and R5 each independently is methyl, hydroxymethyl or cyano, R2 and R4 are always different from one another and each independently is alkyl with 1 to 10 carbon atoms optionally substituted by alkoxy with 1 to 4 carbon atoms, fluorine, chlorine or N-methyl-benzylamino, R3 is nitro, chlorine, trifluoromethyl, or =N-O-N=, and n is 1 or 2, and (B) about 10 to 200 parts by weight of a .beta.-blocker without a local anesthetic action.