FUSED AROMATIC OXAZEPINONES, THIAZEPINONES, DIAZEPINONES AND SULFUR ANALOGS THEREOF

Disclosed are aromatic oxazepine, thiazepine or diazepine compounds of the formula: (II) (wherein A is an aromatic ring, e.g., benzene, naphthalene, quinoline or pyridine, Y is halogen, alkyl, alkoxy, dialkylamino, nitro or trifluoromethyl, E is O, S or N-alkyl, B is O or S, R is alkyl, cycloalkyl or phenyl-alkyl in which phenyl may optionally be substituted, D is optionally alkyl-substituted alkylene, X is Cl,Br,CN or phthalimido) which are useful as intermediates for producing antihistamic and antiallergic compounds of the formula: (I) (wherein Z is NR1R2, pyrazol-1-yl, imidazol-1-yl, imidazol-2-yl or 4,5-dihydro-1H-imidazol-2-yl, R1 and R2 are hydrogen, alkyl, cycloalkyl, phenylloweralkyl or R1 and R2 together with the adjacent nitrogen atoms form a heterocyclicamino group, and the other symbols are as defined above).