PHARMACEUTICAL COMPOSITIONS CONTAINING BENZIMIDAZOLE COMPOUNDS

A pharmaceutical preparation containing as active ingredient a compound of the formula < IMG > Ia or a therapeutically acceptable salt thereof, in which formula R1 and R2 are the same or different and each selected from the group consisting of H, -COOCH3, -COOC2H5, alkyl containing 1 to 7 carbon atoms, halogen, alkoxy containing 1 to 5 carbon atoms, and alkanoyl containing 1 to 4 carbon atoms; and R3, R4 and R5, which are the same or different, are each selected from the group consisting of H, CH3, OCH3, OC2H5, OCH2CH2OCH3, and OCH2CH2OCH2CH3; provided that (a) at least one of R3, R4 and R5 is selected from the group consisting of CH3, OCH3, OC2H5, OCH2CH2OCH3, and OCH2CH2OCH2CH3, and (b) when two of R3, R4 and R5 are H, then the remaining radical R3, R4 or R5 is selected from the group consisting of OCH3, OC2H5, OCH2CH2OCH3, and OCH2CH2OCH2CH3; in association with a pharmaceutically acceptable carrier, the use of the compounds for inhibiting gastric acid secretion; compounds included in the formula Ia, and processes for their preparation.