BRAIN IMAGING RADIOPHARMACEUTICALS

BRAIN IMAGING RADIOPHARMACEUTICALS A compound of the structure: wherein each R' is independently a hydrogen atom, an alkyl group or X, and at least one of the groups R' is X, m is 0 or 1, Z is the anion of a strong mineral acid, b is an integer of 2 or greater and X has the formula: where...

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Bibliographische Detailangaben
Hauptverfasser:	KRAMER, ALFRED V, ZEMYAN, SUSAN E, BURNS, HUGH D, DANNALS, ROBERT F, EPPS, LEON A
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	BRAIN IMAGING RADIOPHARMACEUTICALS A compound of the structure: wherein each R' is independently a hydrogen atom, an alkyl group or X, and at least one of the groups R' is X, m is 0 or 1, Z is the anion of a strong mineral acid, b is an integer of 2 or greater and X has the formula: where R" and R''' are independently hydrogen atoms or alkyl groups, Ar is an aromatic group, and a, d and n are integers. The compounds are usefully converted to technetium-99m complexes. The technetium-99m complexes are useful in brain perfusion imaging.