CARBOXIMIDE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND MEDICINES CONTAINING SAME

The carboximide derivatives of the formula: < IMG > and pharmaceutically acceptable salts thereof; wherein X represents a group of the formula: < IMG > , a group of the formula: < IMG > , a group of the formula: < IMG > , a group of the formula: < IMG > , a group of the formula: < IMG > , a group of the formula < IMG > , a group of the formula: < IMG > , a group of the formula: < IMG > , a group of the formula: < IMG > , a group of the formula: < IMG > , a group of the formula: < IMG > , or a group of the formula: < IMG > ; Z represents a hydrogen atom or a group of the formula: < IMG > wherein R represents an alkyl group having 1 to 16 carbon atoms, a group of the formula < IMG > wherein n is an integer of from 0 to 2, and A is hydrogen atom, a lower alkyl group, a lower alkoxy group of a halogen atom, a cycloalkyl group having 3 to 10 carbon atoms, an alkenyl group having 2 to 16 carbon atoms, a cinnamyl group, a pyridyl group or an amino group of the formula < IMG > wherein R1 and R2 are the same or different, and each represent an alkyl group, hydrogen atom or a cycloalkyl group; Y represents an alkyl group of 1 to 6 carbon atoms of the formula < IMG > wherein p is an integer of from 0 to 2, and X1 and X2 are the same or different, and each represent hydrogen atom, a lower alkyl group, a lower alkoxy group, a halogen atom, a trifluoromethyl group, an unsubstituted pyridyl or pyrimidyl group; or a substituted pyridyl or pyrimidyl with one or more lower alkyl groups, lower alkoxy groups or halogen atoms; or a benzothiazolyl group and m represents an integer of 2 or 3 and processes for the production thereof. The derivatives and their pharmaceutically acceptable salts possess hypoglycemic activity and are useful for treating diabetes.