2-QUINOLONE DERIVATIVES

Substituted 2-quinolone derivatives of the general formula < IMG > are described, wherein the groups R1 - R5 are chosen from hydrogen, alkyl, hydrogen, alkoxy, nitro, cyano, halo alkyl and -COOR6 in which R6 is hydrogen or lower alkyl, provided that not all of R1 - R5 are hydrogen. These compo...

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Hauptverfasser:	ENOMOTO, HIROSHI, NOMURA, TADATOSHI, MURASE, MASAO, INOUE, KICHIRO, AOYAGI, YOSHIAKI, ADACHI, MASAHIRO, CHOKAI, SHOICHI, KONO, TATSUHIKO
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Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	ENOMOTO, HIROSHI NOMURA, TADATOSHI MURASE, MASAO INOUE, KICHIRO AOYAGI, YOSHIAKI ADACHI, MASAHIRO CHOKAI, SHOICHI KONO, TATSUHIKO
description	Substituted 2-quinolone derivatives of the general formula < IMG > are described, wherein the groups R1 - R5 are chosen from hydrogen, alkyl, hydrogen, alkoxy, nitro, cyano, halo alkyl and -COOR6 in which R6 is hydrogen or lower alkyl, provided that not all of R1 - R5 are hydrogen. These compounds find use as remedies for allergic diseases and asthma, and as antitussives and expectorants. Processes for the preparation of these compounds are also described. These compounds have the advantages of being long-acting and orally administerable.
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These compounds find use as remedies for allergic diseases and asthma, and as antitussives and expectorants. Processes for the preparation of these compounds are also described. 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These compounds find use as remedies for allergic diseases and asthma, and as antitussives and expectorants. Processes for the preparation of these compounds are also described. These compounds have the advantages of being long-acting and orally administerable.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record>
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	2-QUINOLONE DERIVATIVES
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