2-QUINOLONE DERIVATIVES

2-QUINOLONE DERIVATIVES

Substituted 2-quinolone derivatives of the general formula < IMG > are described, wherein the groups R1 - R5 are chosen from hydrogen, alkyl, hydrogen, alkoxy, nitro, cyano, halo alkyl and -COOR6 in which R6 is hydrogen or lower alkyl, provided that not all of R1 - R5 are hydrogen. These compo...

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Bibliographische Detailangaben
Hauptverfasser: ENOMOTO, HIROSHI, NOMURA, TADATOSHI, MURASE, MASAO, INOUE, KICHIRO, AOYAGI, YOSHIAKI, ADACHI, MASAHIRO, CHOKAI, SHOICHI, KONO, TATSUHIKO
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Substituted 2-quinolone derivatives of the general formula < IMG > are described, wherein the groups R1 - R5 are chosen from hydrogen, alkyl, hydrogen, alkoxy, nitro, cyano, halo alkyl and -COOR6 in which R6 is hydrogen or lower alkyl, provided that not all of R1 - R5 are hydrogen. These compounds find use as remedies for allergic diseases and asthma, and as antitussives and expectorants. Processes for the preparation of these compounds are also described. These compounds have the advantages of being long-acting and orally administerable.