METHOD FOR PREPARING AN ANTIHYPERTENSIVE AGENT COMPRISING 1-0-ALKYL-2-ACETOYL-SN-GLYCERO-3- PHOSPHOCHOLINE

METHOD FOR PREPARING AN ANTIHYPERTENSIVE AGENT COMPRISING 1-0-ALKYL-2-ACETOYL-SN-GLYCERO-3- PHOSPHOCHOLINE

METHOD FOR PREPARING AN ANTIHYPERTENSIVE AGENT COMPRISING 1-0-ALKYL-2-ACETOYL-SN-GLYCERO-3-PHOSPHOCHOLINE The composition of this invention is I-O-alkyl-2-acetoyl-sn-glycero-3-phosphocholine, having the ionic structural formula: wherein R is saturated alkyl having 9-21 carbon atoms, or salts or hydr...

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Bibliographische Detailangaben
Hauptverfasser: BLANK, MERLE L, SNYDER, FRED L
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:METHOD FOR PREPARING AN ANTIHYPERTENSIVE AGENT COMPRISING 1-0-ALKYL-2-ACETOYL-SN-GLYCERO-3-PHOSPHOCHOLINE The composition of this invention is I-O-alkyl-2-acetoyl-sn-glycero-3-phosphocholine, having the ionic structural formula: wherein R is saturated alkyl having 9-21 carbon atoms, or salts or hydrates of the composition. Preferably R has 13-19 carbon atoms and most preferably R has 15 carbon atoms. The composition of this invention is useful for reducing hypertension in warm-blooded animals, including humans, when administered either orally or by injection or innoculation, e.g., intravenous injection. The composition can be prepared from naturally occurring lipids or synthetically from commercially available material. The invention includes the method of preparing the composition and the composition itself when prepared by that method.