ANTI-EMETIC NORTROPYL(ALKYL)BENZAMIDES

ANTI-EMETIC NORTROPYL(ALKYL)BENZAMIDES

Compounds of the formula (I) and pharmaceutically acceptable salts thereof: (I) wherein: R1 is C1-6 alkyl; R2 is hydrogen or C1-7 acyl; R3 is C1-6 alkyl; R4 is a group CH2R5 wherein R5 is hydrogen, C3-8 cycloalkyl or phenyl optionally substituted by one or two substituents selected from C1-6 alkyl,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: WATTS, ERIC A
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Compounds of the formula (I) and pharmaceutically acceptable salts thereof: (I) wherein: R1 is C1-6 alkyl; R2 is hydrogen or C1-7 acyl; R3 is C1-6 alkyl; R4 is a group CH2R5 wherein R5 is hydrogen, C3-8 cycloalkyl or phenyl optionally substituted by one or two substituents selected from C1-6 alkyl, C1-4 alkoxy, trifluoromethyl and halogen, having useful anti-emetic activity.