LACTAM-N-ACETIC ACIDS AND THEIR AMIDES

New lactam-N-acetic acids and amides thereof having the formula wherein R1 and R2 = H, C1-C4 alkyl, aryl or halogensubstituted aryl, R3 = OH or -NR4R5, R4 and R5 = H, C1-C4alkyl, cycloalkyl, aralkyl or, taken together with the N atom form alkyleneimino, oxa-alkyleneimino, aza-alkyleneimino or N-benz...

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Bibliographische Detailangaben
Hauptverfasser:	MARCHAL, LUCIEN, RODRIGUEZ, LUDOVIC
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	New lactam-N-acetic acids and amides thereof having the formula wherein R1 and R2 = H, C1-C4 alkyl, aryl or halogensubstituted aryl, R3 = OH or -NR4R5, R4 and R5 = H, C1-C4alkyl, cycloalkyl, aralkyl or, taken together with the N atom form alkyleneimino, oxa-alkyleneimino, aza-alkyleneimino or N-benzyl-aza-alkyleneimino, m is 3, 4 or 5, preferably 3, n is 0, 1 or 2, preferably 2; and the pharmaceutically acceptable salts of said acids. Processes for producing these compounds and pharmaceutical compositions containing the same are also given. These compounds show amongst others beneficial activity on the mnemic processes and cardiac activity.