N-(PHOSPHONOACETYL)-L-ASPARTIC ACID COMPOUNDS AND METHODS FOR THEIR PREPARATION

N-(Phosphonoacetyl)-L-aspartic acid (PALA) compounds, especially novel PALA compounds, and methods for their preparation in large amounts are disclosed, These methods include preparation of certain PALA compounds such are PALA dibenzyl ester, disodium PALA, and the cyclohexylamine salt of dibenzyl P...

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Hauptverfasser:	SCHULTZ, ROBERT J, STARKS, FRED W
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	SCHULTZ, ROBERT J STARKS, FRED W
description	N-(Phosphonoacetyl)-L-aspartic acid (PALA) compounds, especially novel PALA compounds, and methods for their preparation in large amounts are disclosed, These methods include preparation of certain PALA compounds such are PALA dibenzyl ester, disodium PALA, and the cyclohexylamine salt of dibenzyl PALA. The compounds of this invention possess antitumor activity in vivo or are intermediates for the production of active antitumor PALA compounds.
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language	eng ; fre
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subjects	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	N-(PHOSPHONOACETYL)-L-ASPARTIC ACID COMPOUNDS AND METHODS FOR THEIR PREPARATION
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