1-ARYLOXY-2,3-EPOXY-PROPANES AND PROCESS FOR THE PRODUCTION THEREOF
of the disclosure: Compounds of the formula wherein R1 and R1' are the same or different and represent hydrogen, an alkyl or alkoxy radical having 1 - 4 carbon atoms, the allyl radical, halogen or the nitro group and R2 represents an acrylic acid radical or acrylic acid nitrile radical of the f...
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Format: | Patent |
Sprache: | eng |
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Zusammenfassung: | of the disclosure: Compounds of the formula wherein R1 and R1' are the same or different and represent hydrogen, an alkyl or alkoxy radical having 1 - 4 carbon atoms, the allyl radical, halogen or the nitro group and R2 represents an acrylic acid radical or acrylic acid nitrile radical of the formulae or wherein R3 represents hydrogen, a (C1-C5)-alkyl radical, an unsubstituted aryl or aryl lower alkyl radical or an aryl or aryl- lower alkyl radical substituted by lower alkyl or lower alkoxy, R4 represents hydrogen or a (C1-C8)-alkyl radical, and R5 represents hydrogen, a lower alkyl or aryl- lower alkyl radical and process for their manufacture. The compounds according to the invention are valuable intermediate products for the production of 1-aryloxy-2-hydroxy-3-aminopropanes that are used as medicaments for the treatment of heart diseases. |
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