SYDNONIMINE N-ACYLDERIVATIVES AND METHOD FOR PREPARING SAME

SYDNONIMINE N-ACYLDERIVATIVES AND METHOD FOR PREPARING SAME

Novel sydnonimine N-acyl derivatives of the formula (I): (I) wherein R is selected from the group consisting of phenyl, .beta.-phenylethyl, d,1-.alpha.-methyl-.beta.-phenylethyl and 1-.alpha.-methyl-.beta.-phenylethyl: R' is selected from the group consisting of hydrogen and phenyl; X is select...

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Hauptverfasser: KELEKHSAEVA, EKATERINA A, OLOVYANISHNIKOVA, ZOYA A, VITVITSKAYA, ANNA S, MASHKOVSKY, MIKHAIL D, PARSHIN, VALERY A, OGORODNIKOVA, VALENTINA V, KHOLODOV, LEONID E, ALTSHULER, ROALD A, YASHUNSKY, VLADIMIR G
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Novel sydnonimine N-acyl derivatives of the formula (I): (I) wherein R is selected from the group consisting of phenyl, .beta.-phenylethyl, d,1-.alpha.-methyl-.beta.-phenylethyl and 1-.alpha.-methyl-.beta.-phenylethyl: R' is selected from the group consisting of hydrogen and phenyl; X is selected from the group consisting of a lower alkyl, phenyl and a group of formula wherein R" is selected from the group consisting of hydrogen, halogen and lower fluorinated alkyl; R"' is selected from the group consisting of hydrogen, halogen and lower alkyl; with the proviso that when X is said group of formula and R', R" and R"' are hydrogen, R is 1-.alpha.-methyl-.beta.-phenylethyl; the compounds possess a psychostimulant activity at a low toxicity and can be used as the active ingredient of medicine.